Matrix Bio
Matrix Bio
I am a working in
I need an animal-free hydrogel to grow and is
I need my gel
Matrix Bio
Accelerating Discovery to Clinical Introduction
Matrix Bio empowers researchers to engineer exceptional hydrogels using robust prediction algorithms and AI-guided design suggestions
I am a working in
I need an animal-free hydrogel to grow and is
I need my gel
Matrix Bio
Revolutionizing 3D Cell Culture for Life Science Research & Development
Unprecedented Control Over Cell Culture in 3D:
Accelerating Discovery to Clinical Introduction
Our Mission
At Matrix Bio, our mission is to enable life science research and development from discovery through clinical introduction by providing scientists with unprecedented control over cell culture in 3D using design software to accelerate hydrogel development.
Our Mission
At Matrix Bio, our mission is to enable life science research and development from discovery through clinical introduction by providing scientists with unprecedented control over cell culture in 3D. Based in the Babraham Accelerator in Cambridge, our team of experts is committed to driving innovation in the field of 3D cell culture.
Our Platform
Matrix Bio is building a groundbreaking platform that radically increases the speed and scale of 3D cell culture development and discovery. Our proprietary technology combines novel high-throughput hydrogel engineering and screening techniques with advanced computational tools, creating a powerful design loop that allows us to rapidly optimize hydrogel formulations for 3D cell growth and develop new design tools for researchers and industry.
Our Approach
Our unique approach harnesses the power of high-throughput hydrogel engineering and computational tools to generate highly optimized hydrogel formulations for the growth of cells in 3 dimensions.
By creating a seamless integration between hydrogel design, synthesis, and characterization, we can quickly identify the ideal conditions for a wide range of cell types and applications. These large datasets inform our tools which we make available to researchers.
Our Approach
Our unique approach harnesses the power of high-throughput hydrogel engineering and computational tools to generate highly optimized hydrogel formulations for the growth of cells in 3 dimensions.
By creating a seamless integration between hydrogel design, synthesis, and characterization, we can quickly identify the ideal conditions for a wide range of cell types and applications.
Our Impact
Matrix Bio's cutting-edge platform is poised to revolutionize the life science industry by:
Accelerating drug discovery and development
Facilitating personalized medicine and targeted therapies
Advancing tissue engineering and regenerative medicine
Enhancing materials science and hydrogel research
Our Impact
Matrix Bio's cutting-edge platform is poised to revolutionize the life science industry by:
Accelerating drug discovery and development
Facilitating personalized medicine and targeted therapies
Advancing tissue engineering and regenerative medicine
Enhancing materials science and hydrogel research
Revolutionise Cell Reprogramming with Optimised Microenvironments
Revolutionise Cell Reprogramming with Optimised Microenvironments
Viral delivery enables reprogramming somatic cells into pluripotent stem cells, unlocking revolutionary potential for regenerative medicine and drug discovery. However, current techniques face major limitations:
Extremely low reprogramming efficiency (~1%) restricts applications
Undefined culture microenvironments poorly recapitulate native niches
Marginal iterative improvements despite intense R&D efforts
Safety concerns around genomic integration
At Matrix Bio, we overcome these constraints through integrated automation, proprietary hydrogel engineering, and machine learning to recreate the extracellular complexity directing cell fate transitions.
Our automated microfluidics rapidly screens thousands of 3D hydrogel formulations to identify matrices that enhance reprogramming yield and control lineage trajectories.Powerful algorithms discern optimal combinations of architectural, mechanical and bioactive cues from these vast datasets.
The key advantages our platform offers include:
10x increased reprogramming efficiency
Defined matrix composition and signalling complexity missing from standard 2D culture underlies improved performance.
Accelerated development timelines
High-throughput automated workflows enable systematic hydrogel optimization 100x faster than iterative approaches
Enhanced scale and safety
Our scaffolds can be fabricated at commercial scales using approved input materials and synthesise protocols. No animal sourcing reduces contamination risks.
Unparalleled insight into reprogramming mechanisms
Multidimensional characterization maps compositional determinants guiding cell state transitions. Machine learning models uncover obscure matrix-mediated effects invisible to humansLet's discuss how applying Matrix Bio's integrated solutions can help overcome significant bottlenecks constraining your viral reprogramming pipelines and platform capabilities. We welcome the opportunity to explore potential partnerships.
Please reach out at solutions@matrixbio.com to schedule an introductory call with our team.
We can share additional details on how advanced niches engineered using our proprietary workflow can enhance efficiency, scale, and control for your critical cell engineering needs.
AI-Assisted Design Tools
Predict a hydrogel's mechanical properties, generate new formulations with optimal swelling ratios, enhance cell compatibility, and much more on the horizon
Mechanical properties prediction
Predict the mechanical behavior of your individual or composite hydrogel with our AI tools. Designed for speed without sacrificing accuracy.
Name: Alginate-Gelatin Composite
Variant: variant1 osteogenic functionality
Swelling Ratio
Tune the swelling ratio of your hydrogels with models trained on extensive datasets. Achieve even more precise predictions after a round of lab experiments.
Biocompatibility
Optimize your hydrogel’s properties for enhanced cell attachment and proliferation. Go beyond standard metrics and utilize machine learning models trained on biocompatibility data from diverse contexts.
Durability
Engineer hydrogels that withstand harsh conditions by improving their durability.
Bioactivity
Engineer hydrogels that withstand harsh conditions by improving their durability.
Adhesion
Design hydrogels with optimal adhesion properties for tailored applications.
Porosity
Fine-tune your hydrogel's porosity for controlled substance transport.
Multi-objective
Optimize multiple performance criteria simultaneously by setting targets for diverse properties and let our models find the optimal balanc
Swelling Ratio
Tune the swelling ratio of your hydrogels with models trained on extensive datasets. Achieve even more precise predictions after a round of lab experiments.
Biocompatibility
Optimize your hydrogel’s properties for enhanced cell attachment and proliferation. Go beyond standard metrics and utilize machine learning models trained on biocompatibility data from diverse contexts.
Durability
Engineer hydrogels that withstand harsh conditions by improving their durability.
Bioactivity
Engineer hydrogels that withstand harsh conditions by improving their durability.
Adhesion
Design hydrogels with optimal adhesion properties for tailored applications.
Porosity
Fine-tune your hydrogel's porosity for controlled substance transport.
Multi-objective
Optimize multiple performance criteria simultaneously by setting targets for diverse properties and let our models find the optimal balanc
Private.
Secure.
Yours.
Matrix Bio safeguards your formulation data while granting you complete ownership of all intellectual property.
Private by design
We acknowledge the invaluable nature of your formulation data, and we commit to its privacy. Access to data is strictly limited to you and the members of your organization.
Safe & secure
With extensive industry experience, we prioritize security. Matrix Bio uses bank-grade security measures to protect your data.
Own your IP
We make IP ownership straightforward. You own the IP, no royalty issues. You simply pay for usage of our platform and tools.